Lin Zhao , Yifan Wu , Xiangqun Yu , Jiang Shi

Hangzhou Academy of Agricultural Sciences, Institute of Crop (Ecology) Research, Hangzhou, 310024, China
Author    Correspondence author
Maize Genomics and Genetics, 2024, Vol. 15, No. 6   doi: 10.5376/mgg.2024.15.0027
Received: 27 Sep., 2024    Accepted: 31 Oct., 2024    Published: 16 Nov., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Zhao L., Wu Y.F., Yu X.Q., and Shi J., 2024, Genetic approaches and breeding strategies for enhancing northern corn leaf blight resistance in maize, Maize Genomics and Genetics, 15(6): 282-292 (doi: 10.5376/mgg.2024.15.0027)

This study explores genetic approaches and breeding strategies to enhance maize resistance to northern corn leaf blight (NCLB), focusing on understanding the genetic basis of resistance and identifying key resistance genes and quantitative trait loci (QTL). The findings indicate that effective NCLB resistance is achieved through both qualitative resistance, primarily controlled by major genes such as Ht1, Ht2, Ht3, and Htn1, and quantitative resistance involving multiple genes. Advanced tools, such as genome-wide association studies (GWAS) and QTL mapping, have enabled precise identification and utilization of resistance genes. Biotechnological innovations, including CRISPR/Cas9 gene editing and RNA interference (RNAi) technology, offer targeted opportunities for resistance enhancement. These integrated strategies have successfully developed maize varieties with improved disease resistance and productivity. This study aims to provide a scientific basis for further genetic improvement and insights into sustainable NCLB management strategies in maize breeding.

Northern corn leaf blight; Maize; Resistance breeding; Gene mining; Marker-assisted selection